#------------------------------------------------------------------------------
#$Date: 2020-09-25 04:08:59 +0300 (Fri, 25 Sep 2020) $
#$Revision: 256746 $
#$URL: file:///home/coder/svn-repositories/cod/cif/1/55/91/1559187.cif $
#------------------------------------------------------------------------------
#
# This file is available in the Crystallography Open Database (COD),
# http://www.crystallography.net/
#
# All data on this site have been placed in the public domain by the
# contributors.
#
data_1559187
loop_
_publ_author_name
'Zhang, Sijing'
'Yang, Zhenghui'
'LI, Minghao'
'Zhang, Qiong'
'Tian, Xiaohe'
'Li, Dandan'
'Li, Shengli'
'Wu, Jieying'
'Tian, Yupeng'
_publ_section_title
;
 A multi-photon fluorescent probe based on quinoline groups for highly
 selective and sensitive detection of lipid droplets
;
_journal_name_full               'The Analyst'
_journal_paper_doi               10.1039/D0AN01847C
_journal_year                    2020
_chemical_formula_moiety         'C21 H22 N2 O'
_chemical_formula_sum            'C21 H22.5 N2 O'
_chemical_formula_weight         318.91
_space_group_crystal_system      triclinic
_space_group_IT_number           2
_space_group_name_Hall           '-P 1'
_space_group_name_H-M_alt        'P -1'
_atom_sites_solution_hydrogens   geom
_atom_sites_solution_primary     dual
_audit_creation_date             2019-07-27
_audit_creation_method
;
Olex2 1.2
(compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506)
;
_audit_update_record
;
2020-06-12 deposited with the CCDC.	2020-09-23 downloaded from the CCDC.
;
_cell_angle_alpha                104.622(2)
_cell_angle_beta                 101.560(2)
_cell_angle_gamma                114.181(2)
_cell_formula_units_Z            4
_cell_length_a                   11.151(2)
_cell_length_b                   12.493(3)
_cell_length_c                   15.327(3)
_cell_measurement_reflns_used    5657
_cell_measurement_temperature    296(2)
_cell_measurement_theta_max      26.998
_cell_measurement_theta_min      2.525
_cell_volume                     1769.6(6)
_computing_cell_refinement       'SAINT v7.68A (Bruker, 2009)'
_computing_data_reduction        'SAINT v7.68A (Bruker, 2009)'
_computing_molecular_graphics    'Olex2 (Dolomanov et al., 2009)'
_computing_publication_material  'Olex2 (Dolomanov et al., 2009)'
_computing_structure_refinement  'XL (Sheldrick, 2008)'
_computing_structure_solution    'ShelXT (Sheldrick, 2015)'
_diffrn_ambient_temperature      296.15
_diffrn_measured_fraction_theta_full 0.990
_diffrn_measured_fraction_theta_max 0.870
_diffrn_measurement_device_type  'Bruker P4'
_diffrn_measurement_method       'ω scans'
_diffrn_radiation_monochromator  graphite
_diffrn_radiation_type           MoK\a
_diffrn_radiation_wavelength     0.71073
_diffrn_reflns_av_R_equivalents  0.0492
_diffrn_reflns_av_unetI/netI     0.0488
_diffrn_reflns_Laue_measured_fraction_full 0.990
_diffrn_reflns_Laue_measured_fraction_max 0.870
_diffrn_reflns_limit_h_max       13
_diffrn_reflns_limit_h_min       -13
_diffrn_reflns_limit_k_max       14
_diffrn_reflns_limit_k_min       -16
_diffrn_reflns_limit_l_max       19
_diffrn_reflns_limit_l_min       -19
_diffrn_reflns_number            13901
_diffrn_reflns_point_group_measured_fraction_full 0.990
_diffrn_reflns_point_group_measured_fraction_max 0.870
_diffrn_reflns_theta_full        25.242
_diffrn_reflns_theta_max         27.447
_diffrn_reflns_theta_min         1.462
_exptl_absorpt_coefficient_mu    0.074
_exptl_absorpt_correction_T_max  0.7455
_exptl_absorpt_correction_T_min  0.5452
_exptl_absorpt_correction_type   none
_exptl_absorpt_process_details
;
SADABS-2008/1 (Bruker,2008) was used for absorption correction.
wR2(int) was 0.1012 before and 0.0352 after correction.
The Ratio of minimum to maximum transmission is 0.7313.
The λ/2 correction factor is 0.0015.
;
_exptl_crystal_colour            yellow
_exptl_crystal_density_diffrn    1.197
_exptl_crystal_description       block-shaped
_exptl_crystal_F_000             682
_exptl_crystal_size_max          0.12
_exptl_crystal_size_mid          0.11
_exptl_crystal_size_min          0.10
_refine_diff_density_max         0.404
_refine_diff_density_min         -0.327
_refine_diff_density_rms         0.064
_refine_ls_extinction_method     none
_refine_ls_goodness_of_fit_ref   1.044
_refine_ls_hydrogen_treatment    constr
_refine_ls_matrix_type           full
_refine_ls_number_parameters     439
_refine_ls_number_reflns         7041
_refine_ls_number_restraints     0
_refine_ls_restrained_S_all      1.044
_refine_ls_R_factor_all          0.0732
_refine_ls_R_factor_gt           0.0566
_refine_ls_shift/su_max          0.003
_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[σ²(Fo²)+(0.0990P)²+0.2002P] where P=(Fo²+2Fc²)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.1580
_refine_ls_wR_factor_ref         0.1757
_reflns_Friedel_coverage         0.000
_reflns_number_gt                5218
_reflns_number_total             7041
_reflns_threshold_expression     'I > 2σ(I)'
_cod_data_source_file            d0an01847c2.cif
_cod_data_source_block           a_CCDC1
_cod_original_formula_sum        'C21 H22.50 N2 O'
_cod_database_code               1559187
_shelx_shelxl_version_number     2014/7
_shelx_space_group_comment
;
The symmetry employed for this shelxl refinement is uniquely defined
by the following loop, which should always be used as a source of
symmetry information in preference to the above space-group names.
They are only intended as comments.
;
_shelx_estimated_absorpt_t_max   0.7455
_shelx_estimated_absorpt_t_min   0.5452
_olex2_refinement_description
;
1. Fixed Uiso
 At 1.2 times of:
  All C(H) groups, All C(H,H) groups
 At 1.5 times of:
  All C(H,H,H) groups, All O(H) groups
2.a Secondary CH2 refined with riding coordinates:
 C3(H3A,H3B), C2(H2A,H2B), C24(H24A,H24B), C23(H23A,H23B)
2.b Aromatic/amide H refined with riding coordinates:
 C12(H12), C11(H11), C14(H14), C33(H33), C7(H7), C19(H19), C20(H20), C15(H15),
 C21(H21), C6(H6), C32(H32), C31(H31), C30(H30), C9(H9), C10(H10), C40(H40),
 C36(H36), C35(H35), C27(H27), C28(H28), C41(H41), C42(H42)
2.c Idealised Me refined as rotating group:
 C4(H4A,H4B,H4C), C1(H1A,H1B,H1C), C25(H25A,H25B,H25C), C22(H22A,H22B,H22C)
2.d Idealised tetrahedral OH refined as rotating group:
 O1(H1), O2(H2)
;
_olex2_submission_special_instructions 'No special instructions were received'
loop_
_space_group_symop_operation_xyz
'x, y, z'
'-x, -y, -z'
loop_
_atom_site_label
_atom_site_type_symbol
_atom_site_fract_x
_atom_site_fract_y
_atom_site_fract_z
_atom_site_U_iso_or_equiv
_atom_site_adp_type
_atom_site_occupancy
_atom_site_site_symmetry_order
_atom_site_calc_flag
_atom_site_refinement_flags_posn
_atom_site_refinement_flags_adp
_atom_site_refinement_flags_occupancy
_atom_site_disorder_assembly
_atom_site_disorder_group
O1 O 0.44360(12) 0.20832(10) 0.62721(9) 0.0538(3) Uani 1 1 d . . . . .
H1 H 0.4691 0.2835 0.6387 0.081 Uiso 1 1 calc GR . . . .
O2 O 0.41212(13) 0.40424(11) 0.77803(8) 0.0554(3) Uani 1 1 d . . . . .
H2 H 0.3642 0.3538 0.7228 0.083 Uiso 1 1 calc GR . . . .
N3 N 0.21051(13) 0.24630(11) 0.59830(9) 0.0399(3) Uani 1 1 d . . . . .
N2 N 0.54992(13) 0.46047(11) 0.64825(8) 0.0410(3) Uani 1 1 d . . . . .
N1 N 0.72401(18) 0.00998(14) 0.19137(11) 0.0627(4) Uani 1 1 d . . . . .
C17 C 0.21448(16) 0.15700(12) 0.52744(10) 0.0399(3) Uani 1 1 d . . . . .
N4 N -0.04852(17) 0.68049(16) 0.99538(11) 0.0654(4) Uani 1 1 d . . . . .
C13 C 0.09852(16) 0.26288(13) 0.58340(11) 0.0409(3) Uani 1 1 d . . . . .
C38 C 0.54429(15) 0.55414(14) 0.71372(10) 0.0415(3) Uani 1 1 d . . . . .
C8 C -0.02143(17) 0.44931(14) 0.75432(11) 0.0443(4) Uani 1 1 d . . . . .
C12 C 0.09394(17) 0.34978(14) 0.66521(11) 0.0448(4) Uani 1 1 d . . . . .
H12 H 0.1753 0.3980 0.7188 0.054 Uiso 1 1 calc R . . . .
C16 C 0.10265(17) 0.08098(13) 0.43813(11) 0.0458(4) Uani 1 1 d . . . . .
C18 C 0.33217(17) 0.13739(14) 0.54414(12) 0.0448(4) Uani 1 1 d . . . . .
C39 C 0.47277(16) 0.52389(15) 0.77861(11) 0.0465(4) Uani 1 1 d . . . . .
C11 C -0.01503(17) 0.36695(14) 0.67075(11) 0.0447(4) Uani 1 1 d . . . . .
H11 H -0.0949 0.3221 0.6160 0.054 Uiso 1 1 calc R . . . .
C34 C 0.62147(16) 0.48994(14) 0.58991(11) 0.0433(4) Uani 1 1 d . . . . .
C14 C -0.01200(17) 0.19608(15) 0.49355(11) 0.0488(4) Uani 1 1 d . . . . .
H14 H -0.0858 0.2137 0.4829 0.059 Uiso 1 1 calc R . . . .
C33 C 0.62694(17) 0.38732(15) 0.52310(11) 0.0470(4) Uani 1 1 d . . . . .
H33 H 0.5726 0.3062 0.5207 0.056 Uiso 1 1 calc R . . . .
C29 C 0.70638(18) 0.29661(15) 0.39664(12) 0.0499(4) Uani 1 1 d . . . . .
C7 C 0.09478(17) 0.53276(15) 0.83734(12) 0.0519(4) Uani 1 1 d . . . . .
H7 H 0.1811 0.5383 0.8393 0.062 Uiso 1 1 calc R . . . .
C19 C 0.3311(2) 0.04047(15) 0.47638(14) 0.0552(4) Uani 1 1 d . . . . .
H19 H 0.4065 0.0252 0.4886 0.066 Uiso 1 1 calc R . . . .
C37 C 0.60968(17) 0.68168(15) 0.72062(12) 0.0492(4) Uani 1 1 d . . . . .
C20 C 0.2196(2) -0.03538(15) 0.38975(14) 0.0589(5) Uani 1 1 d . . . . .
H20 H 0.2218 -0.1001 0.3452 0.071 Uiso 1 1 calc R . . . .
C15 C -0.00986(18) 0.10657(15) 0.42330(12) 0.0513(4) Uani 1 1 d . . . . .
H15 H -0.0833 0.0617 0.3648 0.062 Uiso 1 1 calc R . . . .
C5 C -0.04057(18) 0.60451(16) 0.91708(12) 0.0506(4) Uani 1 1 d . . . . .
C21 C 0.1081(2) -0.01555(15) 0.36990(12) 0.0554(4) Uani 1 1 d . . . . .
H21 H 0.0352 -0.0655 0.3114 0.067 Uiso 1 1 calc R . . . .
C6 C 0.08605(18) 0.60670(16) 0.91600(13) 0.0560(4) Uani 1 1 d . . . . .
H6 H 0.1661 0.6598 0.9701 0.067 Uiso 1 1 calc R . . . .
C32 C 0.70160(19) 0.39796(16) 0.46530(12) 0.0525(4) Uani 1 1 d . . . . .
H32 H 0.7573 0.4795 0.4691 0.063 Uiso 1 1 calc R . . . .
C31 C 0.63545(19) 0.07516(16) 0.31638(12) 0.0536(4) Uani 1 1 d . . . . .
H31 H 0.5838 -0.0084 0.3100 0.064 Uiso 1 1 calc R . . . .
C26 C 0.71632(18) 0.10288(16) 0.25750(11) 0.0505(4) Uani 1 1 d . . . . .
C30 C 0.63137(19) 0.16899(16) 0.38292(12) 0.0528(4) Uani 1 1 d . . . . .
H30 H 0.5765 0.1469 0.4205 0.063 Uiso 1 1 calc R . . . .
C9 C -0.14686(18) 0.44641(17) 0.75572(12) 0.0539(4) Uani 1 1 d . . . . .
H9 H -0.2269 0.3919 0.7019 0.065 Uiso 1 1 calc R . . . .
C10 C -0.15729(19) 0.52121(18) 0.83383(12) 0.0582(5) Uani 1 1 d . . . . .
H10 H -0.2435 0.5163 0.8312 0.070 Uiso 1 1 calc R . . . .
C40 C 0.47014(18) 0.61814(17) 0.84624(12) 0.0564(5) Uani 1 1 d . . . . .
H40 H 0.4257 0.5987 0.8897 0.068 Uiso 1 1 calc R . . . .
C36 C 0.6824(2) 0.70851(16) 0.65656(14) 0.0588(5) Uani 1 1 d . . . . .
H36 H 0.7259 0.7907 0.6581 0.071 Uiso 1 1 calc R . . . .
C35 C 0.68914(19) 0.61594(16) 0.59324(13) 0.0547(4) Uani 1 1 d . . . . .
H35 H 0.7381 0.6345 0.5518 0.066 Uiso 1 1 calc R . . . .
C27 C 0.7924(2) 0.23052(18) 0.27137(14) 0.0632(5) Uani 1 1 d . . . . .
H27 H 0.8478 0.2533 0.2342 0.076 Uiso 1 1 calc R . . . .
C28 C 0.7869(2) 0.32276(17) 0.33884(15) 0.0634(5) Uani 1 1 d . . . . .
H28 H 0.8395 0.4066 0.3461 0.076 Uiso 1 1 calc R . . . .
C3 C -0.1731(2) 0.69437(19) 0.99171(14) 0.0645(5) Uani 1 1 d . . . . .
H3A H -0.2193 0.6827 0.9266 0.077 Uiso 1 1 calc R . . . .
H3B H -0.1445 0.7798 1.0331 0.077 Uiso 1 1 calc R . . . .
C41 C 0.5334(2) 0.74342(18) 0.85080(14) 0.0654(5) Uani 1 1 d . . . . .
H41 H 0.5290 0.8055 0.8964 0.078 Uiso 1 1 calc R . . . .
C42 C 0.6012(2) 0.77463(16) 0.78912(14) 0.0640(5) Uani 1 1 d . . . . .
H42 H 0.6420 0.8577 0.7923 0.077 Uiso 1 1 calc R . . . .
C2 C 0.0622(2) 0.74033(19) 1.09039(14) 0.0696(5) Uani 1 1 d . . . . .
H2A H 0.1083 0.6898 1.0944 0.084 Uiso 1 1 calc R . . . .
H2B H 0.0198 0.7421 1.1398 0.084 Uiso 1 1 calc R . . . .
C24 C 0.7892(2) 0.0375(2) 0.12060(14) 0.0715(6) Uani 1 1 d . . . . .
H24A H 0.7736 0.1018 0.1039 0.086 Uiso 1 1 calc R . . . .
H24B H 0.7436 -0.0384 0.0629 0.086 Uiso 1 1 calc R . . . .
C23 C 0.6535(2) -0.12139(17) 0.18254(15) 0.0718(6) Uani 1 1 d . . . . .
H23A H 0.6610 -0.1232 0.2463 0.086 Uiso 1 1 calc R . . . .
H23B H 0.7024 -0.1630 0.1565 0.086 Uiso 1 1 calc R . . . .
C4 C -0.2757(3) 0.6024(3) 1.02214(19) 0.0884(7) Uani 1 1 d . . . . .
H4A H -0.3030 0.5175 0.9824 0.133 Uiso 1 1 calc GR . . . .
H4B H -0.3568 0.6135 1.0154 0.133 Uiso 1 1 calc GR . . . .
H4C H -0.2328 0.6172 1.0880 0.133 Uiso 1 1 calc GR . . . .
C1 C 0.1680(3) 0.8713(2) 1.10857(19) 0.0911(7) Uani 1 1 d . . . . .
H1A H 0.2122 0.8699 1.0609 0.137 Uiso 1 1 calc GR . . . .
H1B H 0.2374 0.9068 1.1711 0.137 Uiso 1 1 calc GR . . . .
H1C H 0.1230 0.9220 1.1054 0.137 Uiso 1 1 calc GR . . . .
C25 C 0.9441(3) 0.0825(3) 0.1541(2) 0.0933(8) Uani 1 1 d . . . . .
H25A H 0.9798 0.0985 0.1041 0.140 Uiso 1 1 calc GR . . . .
H25B H 0.9606 0.0187 0.1694 0.140 Uiso 1 1 calc GR . . . .
H25C H 0.9906 0.1590 0.2102 0.140 Uiso 1 1 calc GR . . . .
C22 C 0.5021(3) -0.1959(3) 0.1207(2) 0.1123(10) Uani 1 1 d . . . . .
H22A H 0.4928 -0.1944 0.0574 0.168 Uiso 1 1 calc GR . . . .
H22B H 0.4511 -0.1591 0.1480 0.168 Uiso 1 1 calc GR . . . .
H22C H 0.4653 -0.2817 0.1170 0.168 Uiso 1 1 calc GR . . . .
loop_
_atom_type_symbol
_atom_type_description
_atom_type_scat_dispersion_real
_atom_type_scat_dispersion_imag
_atom_type_scat_source
C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
N N 0.0061 0.0033 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
loop_
_geom_angle_atom_site_label_1
_geom_angle_atom_site_label_2
_geom_angle_atom_site_label_3
_geom_angle
_geom_angle_site_symmetry_1
_geom_angle_site_symmetry_3
_geom_angle_publ_flag
C13 N3 C17 119.20(13) . . ?
C34 N2 C38 119.16(13) . . ?
C26 N1 C24 120.92(15) . . ?
C26 N1 C23 121.24(15) . . ?
C23 N1 C24 117.47(15) . . ?
N3 C17 C16 122.07(14) . . ?
N3 C17 C18 119.18(13) . . ?
C18 C17 C16 118.73(13) . . ?
C5 N4 C3 121.93(15) . . ?
C5 N4 C2 121.17(16) . . ?
C3 N4 C2 116.54(15) . . ?
N3 C13 C12 116.54(13) . . ?
N3 C13 C14 121.30(13) . . ?
C14 C13 C12 122.13(14) . . ?
N2 C38 C39 119.28(14) . . ?
N2 C38 C37 122.24(14) . . ?
C37 C38 C39 118.47(14) . . ?
C7 C8 C11 123.05(15) . . ?
C9 C8 C11 120.95(14) . . ?
C9 C8 C7 115.98(14) . . ?
C11 C12 C13 126.59(15) . . ?
C15 C16 C17 116.83(13) . . ?
C15 C16 C21 123.47(15) . . ?
C21 C16 C17 119.70(16) . . ?
O1 C18 C17 121.69(13) . . ?
O1 C18 C19 119.00(15) . . ?
C19 C18 C17 119.26(15) . . ?
O2 C39 C38 121.39(14) . . ?
O2 C39 C40 119.01(15) . . ?
C40 C39 C38 119.54(15) . . ?
C12 C11 C8 126.42(15) . . ?
N2 C34 C33 116.99(14) . . ?
N2 C34 C35 121.27(14) . . ?
C35 C34 C33 121.75(15) . . ?
C15 C14 C13 119.84(15) . . ?
C32 C33 C34 126.54(16) . . ?
C30 C29 C32 123.79(15) . . ?
C28 C29 C32 120.60(15) . . ?
C28 C29 C30 115.60(15) . . ?
C6 C7 C8 122.26(15) . . ?
C18 C19 C20 121.52(17) . . ?
C36 C37 C38 116.82(15) . . ?
C42 C37 C38 120.17(16) . . ?
C42 C37 C36 123.01(16) . . ?
C21 C20 C19 120.60(15) . . ?
C14 C15 C16 120.51(15) . . ?
N4 C5 C6 121.63(15) . . ?
N4 C5 C10 122.19(15) . . ?
C10 C5 C6 116.18(15) . . ?
C20 C21 C16 120.07(16) . . ?
C7 C6 C5 121.73(15) . . ?
C33 C32 C29 127.46(16) . . ?
C30 C31 C26 121.19(16) . . ?
N1 C26 C31 122.06(15) . . ?
N1 C26 C27 121.45(16) . . ?
C27 C26 C31 116.46(15) . . ?
C31 C30 C29 122.62(15) . . ?
C10 C9 C8 122.55(15) . . ?
C9 C10 C5 121.29(16) . . ?
C39 C40 C41 121.10(17) . . ?
C35 C36 C37 120.53(16) . . ?
C36 C35 C34 119.97(16) . . ?
C28 C27 C26 121.17(16) . . ?
C27 C28 C29 122.96(16) . . ?
N4 C3 C4 113.39(18) . . ?
C42 C41 C40 120.54(16) . . ?
C41 C42 C37 120.14(17) . . ?
N4 C2 C1 112.26(19) . . ?
N1 C24 C25 113.98(19) . . ?
N1 C23 C22 115.2(2) . . ?
loop_
_geom_bond_atom_site_label_1
_geom_bond_atom_site_label_2
_geom_bond_distance
_geom_bond_site_symmetry_2
_geom_bond_publ_flag
O1 C18 1.358(2) . ?
O2 C39 1.362(2) . ?
N3 C17 1.3690(18) . ?
N3 C13 1.333(2) . ?
N2 C38 1.3685(19) . ?
N2 C34 1.335(2) . ?
N1 C26 1.380(2) . ?
N1 C24 1.457(2) . ?
N1 C23 1.455(2) . ?
C17 C16 1.421(2) . ?
C17 C18 1.417(2) . ?
N4 C5 1.373(2) . ?
N4 C3 1.461(2) . ?
N4 C2 1.475(3) . ?
C13 C12 1.462(2) . ?
C13 C14 1.417(2) . ?
C38 C39 1.424(2) . ?
C38 C37 1.419(2) . ?
C8 C11 1.461(2) . ?
C8 C7 1.396(2) . ?
C8 C9 1.389(2) . ?
C12 C11 1.332(2) . ?
C16 C15 1.407(2) . ?
C16 C21 1.415(2) . ?
C18 C19 1.376(2) . ?
C39 C40 1.373(2) . ?
C34 C33 1.457(2) . ?
C34 C35 1.422(2) . ?
C14 C15 1.354(2) . ?
C33 C32 1.327(2) . ?
C29 C32 1.455(2) . ?
C29 C30 1.398(2) . ?
C29 C28 1.386(2) . ?
C7 C6 1.369(2) . ?
C19 C20 1.395(3) . ?
C37 C36 1.413(3) . ?
C37 C42 1.405(2) . ?
C20 C21 1.356(3) . ?
C5 C6 1.405(2) . ?
C5 C10 1.400(2) . ?
C31 C26 1.406(2) . ?
C31 C30 1.369(2) . ?
C26 C27 1.399(2) . ?
C9 C10 1.378(2) . ?
C40 C41 1.405(3) . ?
C36 C35 1.349(2) . ?
C27 C28 1.372(2) . ?
C3 C4 1.501(3) . ?
C41 C42 1.359(3) . ?
C2 C1 1.485(3) . ?
C24 C25 1.506(3) . ?
C23 C22 1.497(3) . ?
