#------------------------------------------------------------------------------ #$Date: 2024-11-08 03:41:37 +0200 (Fri, 08 Nov 2024) $ #$Revision: 295828 $ #$URL: file:///home/coder/svn-repositories/cod/cif/7/16/02/7160219.cif $ #------------------------------------------------------------------------------ # # This file is available in the Crystallography Open Database (COD), # http://www.crystallography.net/ # # All data on this site have been placed in the public domain by the # contributors. # data_7160219 loop_ _publ_author_name 'Undamatla, Suribabu' 'Naveen Kumar, Muniganti' 'Mahesh, Shivunapuram' 'Nanubolu, Jagadeesh Babu' 'Maddi, Sridhar Reddy' _publ_section_title ; Pd-Catalyzed ortho-/meta-C-H-annulation of biphenyl amines with enynes through non-rollover cyclometallation ; _journal_name_full 'Organic & Biomolecular Chemistry' _journal_paper_doi 10.1039/D4OB01689K _journal_year 2024 _chemical_formula_moiety 'C33 H24 F4 N2 O2' _chemical_formula_sum 'C33 H24 F4 N2 O2' _chemical_formula_weight 556.54 _space_group_crystal_system monoclinic _space_group_IT_number 14 _space_group_name_Hall '-P 2ybc' _space_group_name_H-M_alt 'P 1 21/c 1' _atom_sites_solution_hydrogens mixed _audit_creation_method SHELXL-2019/3 _audit_update_record ; 2024-06-30 deposited with the CCDC. 2024-11-06 downloaded from the CCDC. ; _cell_angle_alpha 90 _cell_angle_beta 104.697(14) _cell_angle_gamma 90 _cell_formula_units_Z 4 _cell_length_a 10.940(5) _cell_length_b 16.898(8) _cell_length_c 14.590(8) _cell_measurement_reflns_used 5990 _cell_measurement_temperature 294(2) _cell_measurement_theta_max 21.978 _cell_measurement_theta_min 2.271 _cell_volume 2609(2) _computing_cell_refinement 'SAINT (Bruker, 2016)' _computing_data_collection 'APEX3 (Bruker, 2016)' _computing_data_reduction 'Bruker SAINT' _computing_structure_refinement 'SHELXL-2019/2 (Sheldrick, 2019)' _computing_structure_solution 'SHELXT 2018/2 (Sheldrick, 2018)' _diffrn_ambient_temperature 294(2) _diffrn_measured_fraction_theta_full 0.996 _diffrn_measured_fraction_theta_max 0.997 _diffrn_measurement_device_type 'Bruker D8 QUEST PHOTON III C7 HPAD' _diffrn_measurement_method '\w and \f' _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_reflns_av_R_equivalents 0.0907 _diffrn_reflns_av_unetI/netI 0.0799 _diffrn_reflns_Laue_measured_fraction_full 0.996 _diffrn_reflns_Laue_measured_fraction_max 0.997 _diffrn_reflns_limit_h_max 14 _diffrn_reflns_limit_h_min -14 _diffrn_reflns_limit_k_max 21 _diffrn_reflns_limit_k_min -20 _diffrn_reflns_limit_l_max 18 _diffrn_reflns_limit_l_min -18 _diffrn_reflns_number 41526 _diffrn_reflns_point_group_measured_fraction_full 0.996 _diffrn_reflns_point_group_measured_fraction_max 0.997 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 27.498 _diffrn_reflns_theta_min 2.415 _diffrn_source microfocus _exptl_absorpt_coefficient_mu 0.108 _exptl_absorpt_correction_T_max 0.7457 _exptl_absorpt_correction_T_min 0.6590 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details ; SADABS 2016/2: Krause, L., Herbst-Irmer, R., Sheldrick G.M. & Stalke D., J. Appl. Cryst. 48 (2015) 3-10 ; _exptl_crystal_density_diffrn 1.417 _exptl_crystal_description BLOCK _exptl_crystal_F_000 1152 _exptl_crystal_recrystallization_method 'Re-crystallisation from solvent: Acetone' _exptl_crystal_size_max 0.220 _exptl_crystal_size_mid 0.180 _exptl_crystal_size_min 0.160 _refine_diff_density_max 0.171 _refine_diff_density_min -0.199 _refine_diff_density_rms 0.042 _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.004 _refine_ls_hydrogen_treatment mixed _refine_ls_matrix_type full _refine_ls_number_parameters 412 _refine_ls_number_reflns 5950 _refine_ls_number_restraints 120 _refine_ls_restrained_S_all 1.019 _refine_ls_R_factor_all 0.1408 _refine_ls_R_factor_gt 0.0514 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.0549P)^2^+0.4826P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1058 _refine_ls_wR_factor_ref 0.1412 _reflns_Friedel_coverage 0.000 _reflns_number_gt 2929 _reflns_number_total 5950 _reflns_threshold_expression 'I > 2\s(I)' _cod_data_source_file d4ob01689k2.cif _cod_data_source_block KB1371_0m_a _cod_original_sg_symbol_H-M 'P 21/c' _cod_database_code 7160219 _shelx_shelxl_version_number 2019/3 _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _shelx_estimated_absorpt_t_min 0.977 _shelx_estimated_absorpt_t_max 0.983 _shelx_res_file ; TITL KB1371_0m_a.res in P2(1)/c KB1371_0m_a.res created by SHELXL-2019/3 at 13:28:57 on 30-Jun-2024 CELL 0.71073 10.9405 16.8981 14.5898 90.000 104.697 90.000 ZERR 4.000 0.0052 0.0075 0.0075 0.000 0.014 0.000 LATT 1 SYMM -X, 1/2+Y, 1/2-Z SFAC C H F N O UNIT 132 96 16 8 8 TEMP 21 ACTA L.S. 40 BOND $H SIZE 0.22 0.18 0.16 DFIX 0.85 0.02 N2 H2N OMIT -3 55 OMIT 0 4 0 OMIT 0 5 1 OMIT -1 5 1 OMIT -1 2 1 OMIT 0 2 1 OMIT -2 0 4 OMIT -1 3 2 OMIT 1 0 0 OMIT 0 2 0 OMIT 1 0 4 OMIT 1 1 0 SIMU 0.01 C26 O2 O2D C27 F2 F3 F4 O2D F2D F3D F4D DELU 0.01 C26 O2 O2D C27 F2 F3 F4 O2D F2D F3D F4D LIST 6 FMAP 2 PLAN 5 EQIV $1 x, -y+3/2, z-1/2 HTAB N2 O1_$1 CONF WGHT 0.054900 0.482600 FVAR 0.47960 0.73770 C1 1 0.793625 0.620161 0.583366 11.00000 0.04380 0.06351 = 0.04822 0.00500 0.00398 -0.00551 AFIX 43 H1 2 0.856561 0.633225 0.553503 11.00000 -1.20000 AFIX 0 C2 1 0.823067 0.613253 0.680358 11.00000 0.05347 0.06190 = 0.04858 0.00006 -0.00076 -0.00539 AFIX 43 H2 2 0.905441 0.621084 0.716303 11.00000 -1.20000 AFIX 0 C3 1 0.730366 0.594916 0.722474 11.00000 0.06474 0.05978 = 0.03758 -0.00007 0.00528 0.00718 C4 1 0.609488 0.582335 0.672256 11.00000 0.05515 0.08629 = 0.05000 0.00848 0.01577 0.00352 AFIX 43 H4 2 0.547722 0.569537 0.703358 11.00000 -1.20000 AFIX 0 C5 1 0.578783 0.588582 0.575337 11.00000 0.04411 0.07707 = 0.04881 0.00478 0.00679 -0.00113 AFIX 43 H5 2 0.496125 0.579885 0.540453 11.00000 -1.20000 AFIX 0 C6 1 0.671294 0.607884 0.529634 11.00000 0.04103 0.04734 = 0.04272 0.00144 0.00647 0.00155 C7 1 0.747647 0.617588 0.383135 11.00000 0.03334 0.07702 = 0.05109 0.00779 0.00849 0.00478 AFIX 23 H7A 2 0.807865 0.575129 0.404290 11.00000 -1.20000 H7B 2 0.791380 0.667851 0.396452 11.00000 -1.20000 AFIX 0 C8 1 0.683902 0.609606 0.277451 11.00000 0.03586 0.05750 = 0.04378 0.00846 0.00902 0.00508 C9 1 0.693908 0.524564 0.244694 11.00000 0.05611 0.06629 = 0.06479 0.00877 0.02003 0.01423 AFIX 137 H9A 2 0.641884 0.518266 0.181388 11.00000 -1.50000 H9B 2 0.665943 0.488870 0.286373 11.00000 -1.50000 H9C 2 0.780188 0.513095 0.245727 11.00000 -1.50000 AFIX 0 C10 1 0.548347 0.631188 0.272258 11.00000 0.03467 0.04726 = 0.04259 0.00205 0.00810 0.00012 C11 1 0.528162 0.628310 0.368680 11.00000 0.03574 0.04800 = 0.04477 0.00144 0.00540 -0.00154 C12 1 0.467789 0.655509 0.191267 11.00000 0.03630 0.04620 = 0.04089 0.00124 0.00766 0.00000 C13 1 0.516747 0.663767 0.105832 11.00000 0.04102 0.04494 = 0.04390 0.00664 0.01218 0.00776 C14 1 0.648341 0.673911 0.119068 11.00000 0.04317 0.04680 = 0.05046 0.01002 0.01477 0.00747 C15 1 0.733275 0.669061 0.217943 11.00000 0.03696 0.06831 = 0.05328 0.00774 0.01181 0.00053 AFIX 23 H15A 2 0.738776 0.720745 0.247643 11.00000 -1.20000 H15B 2 0.817569 0.653760 0.214800 11.00000 -1.20000 AFIX 0 C16 1 0.697336 0.687473 0.042206 11.00000 0.04890 0.05430 = 0.06274 0.01222 0.02339 0.00661 AFIX 43 H16 2 0.783952 0.694503 0.051627 11.00000 -1.20000 AFIX 0 C17 1 0.619722 0.690764 -0.048461 11.00000 0.06366 0.06051 = 0.05427 0.01445 0.02793 0.01170 AFIX 43 H17 2 0.653146 0.702076 -0.099581 11.00000 -1.20000 AFIX 0 C18 1 0.492319 0.677122 -0.062400 11.00000 0.06088 0.05922 = 0.04226 0.00822 0.01467 0.01308 AFIX 43 H18 2 0.440457 0.677903 -0.123718 11.00000 -1.20000 AFIX 0 C19 1 0.439432 0.662259 0.012623 11.00000 0.04744 0.04387 = 0.04072 0.00295 0.01200 0.01066 C20 1 0.306681 0.631564 -0.012289 11.00000 0.04809 0.04883 = 0.03407 0.00152 0.00758 0.00610 C21 1 0.291366 0.550119 -0.004596 11.00000 0.05896 0.05622 = 0.04923 0.00175 0.01110 0.00976 AFIX 43 H21 2 0.361855 0.519071 0.021301 11.00000 -1.20000 AFIX 0 C22 1 0.175519 0.514491 -0.034069 11.00000 0.07675 0.04938 = 0.06245 -0.00044 0.01848 -0.00406 AFIX 43 H22 2 0.167248 0.460225 -0.026878 11.00000 -1.20000 AFIX 0 C23 1 0.071618 0.560042 -0.074433 11.00000 0.05954 0.06394 = 0.05813 -0.00295 0.00724 -0.01051 AFIX 43 H23 2 -0.006912 0.536126 -0.096543 11.00000 -1.20000 AFIX 0 C24 1 0.082831 0.640378 -0.082347 11.00000 0.05174 0.05780 = 0.04956 -0.00013 0.00177 0.00138 AFIX 43 H24 2 0.011667 0.670587 -0.109101 11.00000 -1.20000 AFIX 0 C25 1 0.199670 0.677092 -0.050723 11.00000 0.04706 0.04614 = 0.03400 -0.00048 0.00465 0.00327 C27 1 0.154631 0.899095 -0.041382 11.00000 0.06346 0.06277 = 0.08542 -0.00411 0.02315 0.00868 C28 1 0.336384 0.682067 0.188697 11.00000 0.03636 0.05141 = 0.03257 0.00043 0.00487 0.00194 C29 1 0.307867 0.761687 0.184342 11.00000 0.04941 0.05381 = 0.04986 -0.00340 0.01049 0.00098 AFIX 43 H29 2 0.369767 0.798399 0.180648 11.00000 -1.20000 AFIX 0 C30 1 0.188643 0.787539 0.185398 11.00000 0.06661 0.06505 = 0.06275 -0.00155 0.01444 0.02316 AFIX 43 H30 2 0.171123 0.841432 0.184404 11.00000 -1.20000 AFIX 0 C31 1 0.096294 0.733655 0.187911 11.00000 0.04324 0.09803 = 0.06721 -0.00011 0.01508 0.01839 AFIX 43 H31 2 0.015366 0.750948 0.187225 11.00000 -1.20000 AFIX 0 C32 1 0.122468 0.654679 0.191419 11.00000 0.03976 0.08361 = 0.06297 0.00174 0.01342 -0.00181 AFIX 43 H32 2 0.059187 0.618281 0.192765 11.00000 -1.20000 AFIX 0 C33 1 0.242153 0.628573 0.192978 11.00000 0.04497 0.05516 = 0.05440 0.00296 0.01203 0.00149 AFIX 43 H33 2 0.259826 0.574664 0.196931 11.00000 -1.20000 AFIX 0 N1 4 0.644228 0.612883 0.429741 11.00000 0.03420 0.06477 = 0.03801 0.00309 0.00483 -0.00014 N2 4 0.211744 0.760577 -0.053492 11.00000 0.04075 0.04876 = 0.05049 -0.00140 0.00696 0.00522 H2N 2 0.286417 0.780639 -0.047521 11.00000 0.07098 O1 5 0.429864 0.638713 0.392216 11.00000 0.03689 0.08055 = 0.04703 0.00289 0.01185 0.00292 F1 3 0.759631 0.587754 0.819044 11.00000 0.08979 0.10521 = 0.04165 0.00190 0.00879 0.00791 C26 1 0.119266 0.812057 -0.053402 11.00000 0.04568 0.05926 = 0.07748 0.00188 0.00856 0.01003 PART 1 O2 5 0.012595 0.795248 -0.046198 21.00000 0.04753 0.07477 = 0.12384 -0.00267 0.02145 0.00829 F2 3 0.271804 0.909803 0.021371 21.00000 0.06289 0.07187 = 0.08325 -0.01006 0.00822 -0.00880 F3 3 0.169471 0.933617 -0.119008 21.00000 0.17453 0.06624 = 0.07971 0.01037 0.02573 -0.01508 F4 3 0.076899 0.937983 -0.006310 21.00000 0.06350 0.08967 = 0.18893 -0.04193 0.04245 0.01878 PART 2 O2D 5 0.007708 0.799998 -0.104550 -21.00000 0.03579 0.07419 = 0.08230 0.00480 0.00341 0.00986 F2D 3 0.251951 0.916858 -0.036871 -21.00000 0.07857 0.07419 = 0.17011 -0.01015 0.04669 -0.00008 F3D 3 0.065278 0.933015 -0.118602 -21.00000 0.12839 0.07149 = 0.11170 0.03435 0.01906 0.01282 F4D 3 0.107842 0.928918 0.026288 -21.00000 0.11537 0.07844 = 0.09975 -0.01835 0.02958 0.01888 PART 0 HKLF 4 REM KB1371_0m_a.res in P2(1)/c REM wR2 = 0.1412, GooF = S = 1.004, Restrained GooF = 1.019 for all data REM R1 = 0.0514 for 2929 Fo > 4sig(Fo) and 0.1408 for all 5950 data REM 412 parameters refined using 120 restraints END WGHT 0.0549 0.4823 REM Highest difference peak 0.171, deepest hole -0.199, 1-sigma level 0.042 Q1 1 0.4924 0.6966 0.0806 11.00000 0.05 0.17 Q2 1 0.4270 0.5748 0.3835 11.00000 0.05 0.16 Q3 1 0.4649 0.6365 0.0607 11.00000 0.05 0.15 Q4 1 0.3968 0.6666 0.1988 11.00000 0.05 0.15 Q5 1 0.9603 0.6232 0.5189 11.00000 0.05 0.14 ; _shelx_res_checksum 77238 loop_ _space_group_symop_operation_xyz 'x, y, z' '-x, y+1/2, -z+1/2' '-x, -y, -z' 'x, -y-1/2, z-1/2' loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group C1 C 0.79362(19) 0.62016(14) 0.58337(16) 0.0532(6) Uani 1 1 d . . . . . H1 H 0.856561 0.633225 0.553503 0.064 Uiso 1 1 calc R U . . . C2 C 0.8231(2) 0.61325(14) 0.68036(17) 0.0571(6) Uani 1 1 d . . . . . H2 H 0.905441 0.621084 0.716303 0.069 Uiso 1 1 calc R U . . . C3 C 0.7304(2) 0.59492(15) 0.72247(16) 0.0554(6) Uani 1 1 d . . . . . C4 C 0.6095(2) 0.58233(16) 0.67226(18) 0.0634(7) Uani 1 1 d . . . . . H4 H 0.547722 0.569537 0.703358 0.076 Uiso 1 1 calc R U . . . C5 C 0.5788(2) 0.58858(15) 0.57534(17) 0.0576(7) Uani 1 1 d . . . . . H5 H 0.496125 0.579885 0.540453 0.069 Uiso 1 1 calc R U . . . C6 C 0.67129(18) 0.60788(13) 0.52963(15) 0.0444(5) Uani 1 1 d . . . . . C7 C 0.74765(18) 0.61759(15) 0.38314(16) 0.0542(6) Uani 1 1 d . . . . . H7A H 0.807865 0.575129 0.404290 0.065 Uiso 1 1 calc R U . . . H7B H 0.791380 0.667851 0.396452 0.065 Uiso 1 1 calc R U . . . C8 C 0.68390(17) 0.60961(13) 0.27745(15) 0.0459(6) Uani 1 1 d . . . . . C9 C 0.6939(2) 0.52456(15) 0.24469(18) 0.0615(7) Uani 1 1 d . . . . . H9A H 0.641884 0.518266 0.181388 0.092 Uiso 1 1 calc R U . . . H9B H 0.665943 0.488870 0.286373 0.092 Uiso 1 1 calc R U . . . H9C H 0.780188 0.513095 0.245727 0.092 Uiso 1 1 calc R U . . . C10 C 0.54835(17) 0.63119(13) 0.27226(15) 0.0418(5) Uani 1 1 d . . . . . C11 C 0.52816(18) 0.62831(13) 0.36868(15) 0.0437(5) Uani 1 1 d . . . . . C12 C 0.46779(17) 0.65551(12) 0.19127(15) 0.0415(5) Uani 1 1 d . . . . . C13 C 0.51675(18) 0.66377(13) 0.10583(15) 0.0430(5) Uani 1 1 d . . . . . C14 C 0.64834(18) 0.67391(13) 0.11907(16) 0.0463(6) Uani 1 1 d . . . . . C15 C 0.73327(18) 0.66906(15) 0.21794(16) 0.0528(6) Uani 1 1 d . . . . . H15A H 0.738776 0.720745 0.247643 0.063 Uiso 1 1 calc R U . . . H15B H 0.817569 0.653760 0.214800 0.063 Uiso 1 1 calc R U . . . C16 C 0.6973(2) 0.68747(14) 0.04221(17) 0.0536(6) Uani 1 1 d . . . . . H16 H 0.783952 0.694503 0.051627 0.064 Uiso 1 1 calc R U . . . C17 C 0.6197(2) 0.69076(14) -0.04846(18) 0.0571(6) Uani 1 1 d . . . . . H17 H 0.653146 0.702076 -0.099581 0.069 Uiso 1 1 calc R U . . . C18 C 0.4923(2) 0.67712(14) -0.06240(16) 0.0538(6) Uani 1 1 d . . . . . H18 H 0.440457 0.677903 -0.123718 0.065 Uiso 1 1 calc R U . . . C19 C 0.43943(19) 0.66226(13) 0.01262(15) 0.0439(5) Uani 1 1 d . . . . . C20 C 0.30668(19) 0.63156(14) -0.01229(14) 0.0442(5) Uani 1 1 d . . . . . C21 C 0.2914(2) 0.55012(15) -0.00460(16) 0.0553(6) Uani 1 1 d . . . . . H21 H 0.361855 0.519071 0.021301 0.066 Uiso 1 1 calc R U . . . C22 C 0.1755(2) 0.51449(16) -0.03407(18) 0.0627(7) Uani 1 1 d . . . . . H22 H 0.167248 0.460225 -0.026878 0.075 Uiso 1 1 calc R U . . . C23 C 0.0716(2) 0.56004(16) -0.07443(17) 0.0619(7) Uani 1 1 d . . . . . H23 H -0.006912 0.536126 -0.096543 0.074 Uiso 1 1 calc R U . . . C24 C 0.0828(2) 0.64038(15) -0.08235(16) 0.0550(6) Uani 1 1 d . . . . . H24 H 0.011667 0.670587 -0.109101 0.066 Uiso 1 1 calc R U . . . C25 C 0.19967(18) 0.67709(13) -0.05072(14) 0.0434(5) Uani 1 1 d . . . . . C27 C 0.1546(3) 0.89910(17) -0.0414(2) 0.0698(8) Uani 1 1 d . U . . . C28 C 0.33638(17) 0.68207(13) 0.18870(14) 0.0408(5) Uani 1 1 d . . . . . C29 C 0.3079(2) 0.76169(15) 0.18434(15) 0.0514(6) Uani 1 1 d . . . . . H29 H 0.369767 0.798399 0.180648 0.062 Uiso 1 1 calc R U . . . C30 C 0.1886(2) 0.78754(17) 0.18540(17) 0.0652(7) Uani 1 1 d . . . . . H30 H 0.171123 0.841432 0.184404 0.078 Uiso 1 1 calc R U . . . C31 C 0.0963(2) 0.7337(2) 0.18791(18) 0.0693(8) Uani 1 1 d . . . . . H31 H 0.015366 0.750948 0.187225 0.083 Uiso 1 1 calc R U . . . C32 C 0.1225(2) 0.65468(18) 0.19142(17) 0.0620(7) Uani 1 1 d . . . . . H32 H 0.059187 0.618281 0.192765 0.074 Uiso 1 1 calc R U . . . C33 C 0.24215(19) 0.62857(15) 0.19298(16) 0.0516(6) Uani 1 1 d . . . . . H33 H 0.259826 0.574664 0.196931 0.062 Uiso 1 1 calc R U . . . N1 N 0.64423(14) 0.61288(11) 0.42974(12) 0.0464(5) Uani 1 1 d . . . . . N2 N 0.21174(16) 0.76058(12) -0.05349(13) 0.0475(5) Uani 1 1 d D . . . . H2N H 0.2864(17) 0.7806(14) -0.0475(17) 0.071(8) Uiso 1 1 d D . . . . O1 O 0.42986(12) 0.63871(10) 0.39222(10) 0.0546(4) Uani 1 1 d . . . . . F1 F 0.75963(14) 0.58775(10) 0.81904(10) 0.0803(5) Uani 1 1 d . . . . . C26 C 0.1193(2) 0.81206(16) -0.05340(19) 0.0621(7) Uani 1 1 d . U . . . O2 O 0.0126(3) 0.7952(2) -0.0462(4) 0.0821(12) Uani 0.738(7) 1 d . U P A 1 F2 F 0.2718(3) 0.9098(2) 0.0214(3) 0.0745(9) Uani 0.738(7) 1 d . U P A 1 F3 F 0.1695(6) 0.93362(16) -0.1190(2) 0.1080(15) Uani 0.738(7) 1 d . U P A 1 F4 F 0.0769(5) 0.9380(5) -0.0063(5) 0.112(2) Uani 0.738(7) 1 d . U P A 1 O2D O 0.0077(8) 0.8000(7) -0.1045(8) 0.066(3) Uani 0.262(7) 1 d . U P A 2 F2D F 0.2520(11) 0.9169(7) -0.0369(13) 0.105(3) Uani 0.262(7) 1 d . U P A 2 F3D F 0.0653(13) 0.9330(5) -0.1186(7) 0.106(3) Uani 0.262(7) 1 d . U P A 2 F4D F 0.1078(18) 0.9289(16) 0.0263(13) 0.097(4) Uani 0.262(7) 1 d . U P A 2 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 C1 0.0438(12) 0.0635(17) 0.0482(15) 0.0050(12) 0.0040(10) -0.0055(11) C2 0.0535(13) 0.0619(17) 0.0486(15) 0.0001(12) -0.0008(11) -0.0054(11) C3 0.0647(15) 0.0598(17) 0.0376(14) -0.0001(12) 0.0053(12) 0.0072(12) C4 0.0552(14) 0.086(2) 0.0500(16) 0.0085(14) 0.0158(12) 0.0035(13) C5 0.0441(12) 0.0771(19) 0.0488(15) 0.0048(13) 0.0068(11) -0.0011(11) C6 0.0410(11) 0.0473(14) 0.0427(13) 0.0014(10) 0.0065(10) 0.0016(9) C7 0.0333(11) 0.0770(18) 0.0511(15) 0.0078(12) 0.0085(10) 0.0048(11) C8 0.0359(11) 0.0575(16) 0.0438(13) 0.0085(11) 0.0090(9) 0.0051(10) C9 0.0561(14) 0.0663(19) 0.0648(17) 0.0088(14) 0.0200(12) 0.0142(12) C10 0.0347(10) 0.0473(14) 0.0426(13) 0.0020(10) 0.0081(9) 0.0001(9) C11 0.0357(11) 0.0480(14) 0.0448(13) 0.0014(11) 0.0054(9) -0.0015(9) C12 0.0363(10) 0.0462(14) 0.0409(13) 0.0012(10) 0.0077(9) 0.0000(9) C13 0.0410(11) 0.0449(14) 0.0439(13) 0.0066(10) 0.0122(10) 0.0078(9) C14 0.0432(11) 0.0468(15) 0.0505(14) 0.0100(11) 0.0148(10) 0.0075(10) C15 0.0370(11) 0.0683(17) 0.0533(15) 0.0077(12) 0.0118(10) 0.0005(10) C16 0.0489(12) 0.0543(16) 0.0627(17) 0.0122(12) 0.0234(12) 0.0066(11) C17 0.0637(15) 0.0605(17) 0.0543(16) 0.0144(12) 0.0279(12) 0.0117(12) C18 0.0609(14) 0.0592(17) 0.0423(14) 0.0082(11) 0.0147(11) 0.0131(11) C19 0.0474(12) 0.0439(14) 0.0407(13) 0.0030(10) 0.0120(10) 0.0107(10) C20 0.0481(12) 0.0488(16) 0.0341(12) 0.0015(10) 0.0076(9) 0.0061(10) C21 0.0590(14) 0.0562(19) 0.0492(15) 0.0017(12) 0.0111(11) 0.0098(12) C22 0.0767(17) 0.0494(17) 0.0625(17) -0.0004(13) 0.0185(14) -0.0041(13) C23 0.0595(15) 0.064(2) 0.0581(17) -0.0030(13) 0.0072(12) -0.0105(13) C24 0.0517(13) 0.0578(19) 0.0496(15) -0.0001(12) 0.0018(11) 0.0014(11) C25 0.0471(12) 0.0461(16) 0.0340(12) -0.0005(10) 0.0046(9) 0.0033(10) C27 0.0635(17) 0.0628(19) 0.085(2) -0.0041(16) 0.0231(16) 0.0087(14) C28 0.0364(10) 0.0514(16) 0.0326(12) 0.0004(10) 0.0049(8) 0.0019(10) C29 0.0494(12) 0.0538(18) 0.0499(15) -0.0034(11) 0.0105(10) 0.0010(11) C30 0.0666(16) 0.0650(19) 0.0628(17) -0.0016(14) 0.0144(13) 0.0232(14) C31 0.0432(13) 0.098(2) 0.0672(18) -0.0001(16) 0.0151(12) 0.0184(15) C32 0.0398(12) 0.084(2) 0.0630(17) 0.0017(14) 0.0134(11) -0.0018(12) C33 0.0450(12) 0.0552(16) 0.0544(15) 0.0030(12) 0.0120(10) 0.0015(11) N1 0.0342(9) 0.0648(13) 0.0380(11) 0.0031(9) 0.0048(7) -0.0001(8) N2 0.0407(10) 0.0488(14) 0.0505(12) -0.0014(9) 0.0070(8) 0.0052(9) O1 0.0369(8) 0.0805(12) 0.0470(9) 0.0029(8) 0.0119(7) 0.0029(7) F1 0.0898(10) 0.1052(13) 0.0416(9) 0.0019(8) 0.0088(7) 0.0079(9) C26 0.0457(13) 0.0593(17) 0.0775(18) 0.0019(13) 0.0086(12) 0.0100(12) O2 0.0475(16) 0.075(2) 0.124(4) -0.003(3) 0.021(2) 0.0083(13) F2 0.0629(14) 0.0719(17) 0.083(2) -0.0101(17) 0.0082(14) -0.0088(11) F3 0.175(4) 0.0662(17) 0.080(2) 0.0104(14) 0.026(2) -0.015(2) F4 0.064(2) 0.090(3) 0.189(6) -0.042(4) 0.042(3) 0.0188(18) O2D 0.036(3) 0.074(5) 0.082(6) 0.005(6) 0.003(4) 0.010(3) F2D 0.079(5) 0.074(5) 0.170(10) -0.010(8) 0.047(6) 0.000(4) F3D 0.128(7) 0.071(4) 0.112(5) 0.034(4) 0.019(5) 0.013(5) F4D 0.115(9) 0.078(6) 0.100(6) -0.018(5) 0.030(6) 0.019(7) loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' F F 0.0171 0.0103 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' N N 0.0061 0.0033 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C2 C1 C6 120.7(2) . . ? C2 C1 H1 119.6 . . ? C6 C1 H1 119.6 . . ? C3 C2 C1 118.8(2) . . ? C3 C2 H2 120.6 . . ? C1 C2 H2 120.6 . . ? C2 C3 C4 122.2(2) . . ? C2 C3 F1 118.9(2) . . ? C4 C3 F1 118.9(2) . . ? C3 C4 C5 119.7(2) . . ? C3 C4 H4 120.2 . . ? C5 C4 H4 120.2 . . ? C4 C5 C6 119.8(2) . . ? C4 C5 H5 120.1 . . ? C6 C5 H5 120.1 . . ? C1 C6 C5 118.8(2) . . ? C1 C6 N1 119.62(19) . . ? C5 C6 N1 121.52(18) . . ? N1 C7 C8 104.80(16) . . ? N1 C7 H7A 110.8 . . ? C8 C7 H7A 110.8 . . ? N1 C7 H7B 110.8 . . ? C8 C7 H7B 110.8 . . ? H7A C7 H7B 108.9 . . ? C10 C8 C15 107.43(17) . . ? C10 C8 C9 111.04(17) . . ? C15 C8 C9 112.37(19) . . ? C10 C8 C7 102.72(17) . . ? C15 C8 C7 112.46(18) . . ? C9 C8 C7 110.37(18) . . ? C8 C9 H9A 109.5 . . ? C8 C9 H9B 109.5 . . ? H9A C9 H9B 109.5 . . ? C8 C9 H9C 109.5 . . ? H9A C9 H9C 109.5 . . ? H9B C9 H9C 109.5 . . ? C12 C10 C11 128.48(18) . . ? C12 C10 C8 122.24(19) . . ? C11 C10 C8 109.03(16) . . ? O1 C11 N1 125.3(2) . . ? O1 C11 C10 128.10(18) . . ? N1 C11 C10 106.59(17) . . ? C10 C12 C13 118.08(18) . . ? C10 C12 C28 121.59(19) . . ? C13 C12 C28 120.00(17) . . ? C19 C13 C14 118.40(19) . . ? C19 C13 C12 123.62(18) . . ? C14 C13 C12 117.98(18) . . ? C16 C14 C13 120.1(2) . . ? C16 C14 C15 120.99(19) . . ? C13 C14 C15 118.91(19) . . ? C14 C15 C8 111.22(17) . . ? C14 C15 H15A 109.4 . . ? C8 C15 H15A 109.4 . . ? C14 C15 H15B 109.4 . . ? C8 C15 H15B 109.4 . . ? H15A C15 H15B 108.0 . . ? C14 C16 C17 121.0(2) . . ? C14 C16 H16 119.5 . . ? C17 C16 H16 119.5 . . ? C18 C17 C16 119.3(2) . . ? C18 C17 H17 120.4 . . ? C16 C17 H17 120.4 . . ? C17 C18 C19 121.6(2) . . ? C17 C18 H18 119.2 . . ? C19 C18 H18 119.2 . . ? C18 C19 C13 119.4(2) . . ? C18 C19 C20 116.42(19) . . ? C13 C19 C20 123.28(19) . . ? C25 C20 C21 118.11(19) . . ? C25 C20 C19 124.8(2) . . ? C21 C20 C19 116.82(18) . . ? C22 C21 C20 121.9(2) . . ? C22 C21 H21 119.0 . . ? C20 C21 H21 119.0 . . ? C21 C22 C23 119.1(2) . . ? C21 C22 H22 120.4 . . ? C23 C22 H22 120.4 . . ? C24 C23 C22 120.6(2) . . ? C24 C23 H23 119.7 . . ? C22 C23 H23 119.7 . . ? C23 C24 C25 120.6(2) . . ? C23 C24 H24 119.7 . . ? C25 C24 H24 119.7 . . ? C24 C25 C20 119.7(2) . . ? C24 C25 N2 121.25(19) . . ? C20 C25 N2 119.05(18) . . ? F4 C27 F3 110.8(4) . . ? F2D C27 F4D 114.0(12) . . ? F4 C27 F2 105.4(4) . . ? F3 C27 F2 102.4(3) . . ? F2D C27 F3D 113.8(8) . . ? F4D C27 F3D 96.9(8) . . ? F2D C27 C26 119.3(6) . . ? F4 C27 C26 111.6(5) . . ? F3 C27 C26 114.3(3) . . ? F4D C27 C26 108.6(12) . . ? F2 C27 C26 111.6(3) . . ? F3D C27 C26 101.3(4) . . ? C29 C28 C33 118.48(19) . . ? C29 C28 C12 119.88(18) . . ? C33 C28 C12 121.6(2) . . ? C28 C29 C30 120.8(2) . . ? C28 C29 H29 119.6 . . ? C30 C29 H29 119.6 . . ? C31 C30 C29 119.8(2) . . ? C31 C30 H30 120.1 . . ? C29 C30 H30 120.1 . . ? C32 C31 C30 120.2(2) . . ? C32 C31 H31 119.9 . . ? C30 C31 H31 119.9 . . ? C31 C32 C33 120.3(2) . . ? C31 C32 H32 119.9 . . ? C33 C32 H32 119.9 . . ? C32 C33 C28 120.4(2) . . ? C32 C33 H33 119.8 . . ? C28 C33 H33 119.8 . . ? C11 N1 C6 126.52(17) . . ? C11 N1 C7 112.56(18) . . ? C6 N1 C7 119.86(16) . . ? C26 N2 C25 124.9(2) . . ? C26 N2 H2N 116.1(17) . . ? C25 N2 H2N 118.5(17) . . ? O2 C26 N2 125.8(3) . . ? O2D C26 N2 120.6(6) . . ? O2 C26 C27 115.6(3) . . ? O2D C26 C27 113.6(5) . . ? N2 C26 C27 117.4(2) . . ? loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag C1 C2 1.374(3) . ? C1 C6 1.384(3) . ? C1 H1 0.9300 . ? C2 C3 1.348(3) . ? C2 H2 0.9300 . ? C3 C4 1.356(3) . ? C3 F1 1.369(3) . ? C4 C5 1.372(3) . ? C4 H4 0.9300 . ? C5 C6 1.385(3) . ? C5 H5 0.9300 . ? C6 N1 1.414(3) . ? C7 N1 1.463(3) . ? C7 C8 1.529(3) . ? C7 H7A 0.9700 . ? C7 H7B 0.9700 . ? C8 C10 1.510(3) . ? C8 C15 1.514(3) . ? C8 C9 1.527(3) . ? C9 H9A 0.9600 . ? C9 H9B 0.9600 . ? C9 H9C 0.9600 . ? C10 C12 1.347(3) . ? C10 C11 1.479(3) . ? C11 O1 1.222(2) . ? C11 N1 1.378(2) . ? C12 C13 1.483(3) . ? C12 C28 1.497(3) . ? C13 C19 1.408(3) . ? C13 C14 1.414(3) . ? C14 C16 1.379(3) . ? C14 C15 1.507(3) . ? C15 H15A 0.9700 . ? C15 H15B 0.9700 . ? C16 C17 1.380(3) . ? C16 H16 0.9300 . ? C17 C18 1.376(3) . ? C17 H17 0.9300 . ? C18 C19 1.385(3) . ? C18 H18 0.9300 . ? C19 C20 1.498(3) . ? C20 C25 1.394(3) . ? C20 C21 1.394(3) . ? C21 C22 1.370(3) . ? C21 H21 0.9300 . ? C22 C23 1.375(3) . ? C22 H22 0.9300 . ? C23 C24 1.371(3) . ? C23 H23 0.9300 . ? C24 C25 1.390(3) . ? C24 H24 0.9300 . ? C25 N2 1.418(3) . ? C27 F2D 1.092(10) . ? C27 F4 1.280(8) . ? C27 F3 1.320(4) . ? C27 F4D 1.32(2) . ? C27 F2 1.385(5) . ? C27 F3D 1.412(10) . ? C27 C26 1.520(4) . ? C28 C29 1.379(3) . ? C28 C33 1.384(3) . ? C29 C30 1.379(3) . ? C29 H29 0.9300 . ? C30 C31 1.367(4) . ? C30 H30 0.9300 . ? C31 C32 1.363(4) . ? C31 H31 0.9300 . ? C32 C33 1.376(3) . ? C32 H32 0.9300 . ? C33 H33 0.9300 . ? N2 C26 1.335(3) . ? N2 H2N 0.868(16) . ? C26 O2 1.231(4) . ? C26 O2D 1.275(9) . ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A _geom_hbond_publ_flag N2 H2N O1 0.868(16) 2.407(19) 3.190(3) 150(2) 4_575 yes loop_ _geom_torsion_atom_site_label_1 _geom_torsion_atom_site_label_2 _geom_torsion_atom_site_label_3 _geom_torsion_atom_site_label_4 _geom_torsion _geom_torsion_site_symmetry_1 _geom_torsion_site_symmetry_2 _geom_torsion_site_symmetry_3 _geom_torsion_site_symmetry_4 _geom_torsion_publ_flag C6 C1 C2 C3 -0.5(4) . . . . ? C1 C2 C3 C4 0.7(4) . . . . ? C1 C2 C3 F1 179.8(2) . . . . ? C2 C3 C4 C5 -0.3(4) . . . . ? F1 C3 C4 C5 -179.4(2) . . . . ? C3 C4 C5 C6 -0.2(4) . . . . ? C2 C1 C6 C5 0.1(3) . . . . ? C2 C1 C6 N1 -178.0(2) . . . . ? C4 C5 C6 C1 0.3(4) . . . . ? C4 C5 C6 N1 178.3(2) . . . . ? N1 C7 C8 C10 20.2(2) . . . . ? N1 C7 C8 C15 135.35(19) . . . . ? N1 C7 C8 C9 -98.3(2) . . . . ? C15 C8 C10 C12 40.2(3) . . . . ? C9 C8 C10 C12 -83.0(3) . . . . ? C7 C8 C10 C12 159.0(2) . . . . ? C15 C8 C10 C11 -134.35(19) . . . . ? C9 C8 C10 C11 102.4(2) . . . . ? C7 C8 C10 C11 -15.6(2) . . . . ? C12 C10 C11 O1 9.3(4) . . . . ? C8 C10 C11 O1 -176.6(2) . . . . ? C12 C10 C11 N1 -169.5(2) . . . . ? C8 C10 C11 N1 4.7(2) . . . . ? C11 C10 C12 C13 171.2(2) . . . . ? C8 C10 C12 C13 -2.2(3) . . . . ? C11 C10 C12 C28 -2.2(3) . . . . ? C8 C10 C12 C28 -175.7(2) . . . . ? C10 C12 C13 C19 157.9(2) . . . . ? C28 C12 C13 C19 -28.6(3) . . . . ? C10 C12 C13 C14 -22.3(3) . . . . ? C28 C12 C13 C14 151.25(19) . . . . ? C19 C13 C14 C16 4.4(3) . . . . ? C12 C13 C14 C16 -175.4(2) . . . . ? C19 C13 C14 C15 -175.1(2) . . . . ? C12 C13 C14 C15 5.0(3) . . . . ? C16 C14 C15 C8 -145.5(2) . . . . ? C13 C14 C15 C8 34.0(3) . . . . ? C10 C8 C15 C14 -53.5(2) . . . . ? C9 C8 C15 C14 68.9(2) . . . . ? C7 C8 C15 C14 -165.83(18) . . . . ? C13 C14 C16 C17 -0.5(3) . . . . ? C15 C14 C16 C17 179.0(2) . . . . ? C14 C16 C17 C18 -2.6(3) . . . . ? C16 C17 C18 C19 1.8(4) . . . . ? C17 C18 C19 C13 2.2(3) . . . . ? C17 C18 C19 C20 -167.4(2) . . . . ? C14 C13 C19 C18 -5.3(3) . . . . ? C12 C13 C19 C18 174.6(2) . . . . ? C14 C13 C19 C20 163.6(2) . . . . ? C12 C13 C19 C20 -16.5(3) . . . . ? C18 C19 C20 C25 -74.6(3) . . . . ? C13 C19 C20 C25 116.2(2) . . . . ? C18 C19 C20 C21 99.0(2) . . . . ? C13 C19 C20 C21 -70.2(3) . . . . ? C25 C20 C21 C22 0.4(3) . . . . ? C19 C20 C21 C22 -173.6(2) . . . . ? C20 C21 C22 C23 1.5(4) . . . . ? C21 C22 C23 C24 -2.1(4) . . . . ? C22 C23 C24 C25 0.8(4) . . . . ? C23 C24 C25 C20 1.2(3) . . . . ? C23 C24 C25 N2 -176.4(2) . . . . ? C21 C20 C25 C24 -1.8(3) . . . . ? C19 C20 C25 C24 171.7(2) . . . . ? C21 C20 C25 N2 175.90(19) . . . . ? C19 C20 C25 N2 -10.6(3) . . . . ? C10 C12 C28 C29 103.1(3) . . . . ? C13 C12 C28 C29 -70.2(3) . . . . ? C10 C12 C28 C33 -75.3(3) . . . . ? C13 C12 C28 C33 111.4(2) . . . . ? C33 C28 C29 C30 0.8(3) . . . . ? C12 C28 C29 C30 -177.6(2) . . . . ? C28 C29 C30 C31 -2.0(4) . . . . ? C29 C30 C31 C32 1.4(4) . . . . ? C30 C31 C32 C33 0.4(4) . . . . ? C31 C32 C33 C28 -1.6(4) . . . . ? C29 C28 C33 C32 1.0(3) . . . . ? C12 C28 C33 C32 179.4(2) . . . . ? O1 C11 N1 C6 -1.4(3) . . . . ? C10 C11 N1 C6 177.45(19) . . . . ? O1 C11 N1 C7 -169.5(2) . . . . ? C10 C11 N1 C7 9.3(2) . . . . ? C1 C6 N1 C11 -157.0(2) . . . . ? C5 C6 N1 C11 24.9(3) . . . . ? C1 C6 N1 C7 10.3(3) . . . . ? C5 C6 N1 C7 -167.7(2) . . . . ? C8 C7 N1 C11 -19.2(2) . . . . ? C8 C7 N1 C6 171.77(18) . . . . ? C24 C25 N2 C26 24.3(3) . . . . ? C20 C25 N2 C26 -153.4(2) . . . . ? C25 N2 C26 O2 3.8(5) . . . . ? C25 N2 C26 O2D -43.1(7) . . . . ? C25 N2 C26 C27 170.8(2) . . . . ? F4 C27 C26 O2 13.6(6) . . . . ? F3 C27 C26 O2 -113.1(6) . . . . ? F2 C27 C26 O2 131.2(5) . . . . ? F2D C27 C26 O2D -145.3(15) . . . . ? F4D C27 C26 O2D 81.8(11) . . . . ? F3D C27 C26 O2D -19.6(10) . . . . ? F2D C27 C26 N2 3.0(12) . . . . ? F4 C27 C26 N2 -154.8(4) . . . . ? F3 C27 C26 N2 78.6(4) . . . . ? F4D C27 C26 N2 -129.9(8) . . . . ? F2 C27 C26 N2 -37.1(4) . . . . ? F3D C27 C26 N2 128.8(6) . . . . ?